I focus on understanding the intricate processes governing chromatin organization, DNA-protein interactions, and gene regulation. My work combines stochastic modelling and computational approaches to explore chromosome-wide target search mechanisms, chromatin dynamics, and the 3D architecture of genomes. Using tools like Hi-C data and multifractal null models, I aim to uncover stable chromatin communities and the principles behind enhancer-insulator pairing.
2024
Umeå: Umeå University 2024
Hedström, Lucas
2024
PRX Life, American Physical Society (APS) 2024, Vol. 2, (3)
Hedström, Lucas; Metzler, Ralf; Lizana, Ludvig
2024
Physical review. E, American Physical Society 2024, Vol. 109, (6)
Hedström, Lucas; Olsson, Peter
2023
New Journal of Physics, Institute of Physics (IOP) 2023, Vol. 25, (3)
Hedström, Lucas; Lizana, Ludvig
Hedström, Lucas; Carcedo Martínez, Antón; Lizana, Ludvig
I supervise and develop modelling labs in several different courses in the physics department in the subject areas of fluid mechanics, biophysical systems, electromagnetism, population dynamics and disease spreading on networks.